I'm on Tiger.
If things like the Load button and Preferences Window are not coming up then you have a permissions problem.
Open your harddrive Icon and go to the Users Folder.
Then open the Shared Folder in there, you will find a folder named Scribe.
Get Info on the Scribe Folder folder and open the Ownership & Permissions > Details section
From the Others Popup Menu select Read and Write
Then Click the "Apply to enclosed items..." Button
Enter your Password
Now your Express Scribe should work as expected.