Audio and picture glitch

[Digigirl]

Just created my first dvd series set. However when I played the first disc in my dvd player there was an audio/picture problem that occurred every few minutes or so, but the glitch does not occur when played on a computer. The audio would cut out and the top of the picture would glitch like a skip in the disc, but the disc is brand new without a scratch on it. Has anyone else had this problem?